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    Important species and taking inventory of oral antidiabetic drugs

    2015/11/30      view:
          Taking sulfonylureas points: mainly by stimulating the pancreatic β cells to produce insulin play a hypoglycemic effect. Islet function in patients with completely destroyed, the poor treatment of this class of drugs. This class of drugs slow onset, it is generally in advance of taking half an hour before a meal, but the role of these drugs for a long time, are easy to cause low blood sugar reactions. 
          We are all human, we must take medicine cure sick, can not be as Wei illness seek medical treatment as classical Lane said. Drug treatment is important, we must in order to achieve the desired effect on the basis of diet and exercise therapy on. In addition to diabetes control the disease through diet therapy and regular exercise outside, glycemic control would require not been taking hypoglycemic agents. Quite a lot of types of hypoglycemic drugs, diabetic patients if their understanding of various antidiabetic drugs, through scientific compatibility, timing quantitative taking reasonable choice according to the disease, in order to reduce or avoid adverse reactions, but also for disease control beneficial. 
          Types of oral hypoglycemic agents 
    Diabetes experts, oral hypoglycemic agents are divided into the following categories: 
          1, promote insulin secretion drugs, such as sulfonylureas, including glibenclamide (glyburide), glipizide (Glipizide, Don Sukhothai, gifted da spirit, glipizide), gliclazide (gliclazide or sustained-release tablets), gliquidone (Gliquidon) and glimepiride (Yousu, etc.), non-sulfonylurea insulin secretion called benzoic acid drugs or insulin secretion drug (glibenclamide Chennai class), such as repaglinide (repaglinide, Corfu to Di), nateglinide (Don force). 
          2, non-insulin secretion drugs, such as biguanide (metformin, Glucophage, Dihua lozenges, America Dikang etc.), glucosidase inhibitors such as acarbose (acarbose, Carbonell flat), voglibose (Basen). 
          3, insulin sensitizers: thiazolidinediones TZDs, including rosiglitazone maleate (Avandia, Donatello, etc.), pioglitazone hydrochloride (Rui Tong, Yi Ting, etc.). 
    Taking elements of various types of oral antidiabetic drugs 
          Taking sulfonylureas points: mainly by stimulating the pancreatic β cells to produce insulin play a hypoglycemic effect. Islet function in patients with completely destroyed, the poor treatment of this class of drugs. This class of drugs slow onset, it is generally in advance of taking half an hour before a meal, but the role of these drugs for a long time, are easy to cause low blood sugar reactions. 
          Non-sulfonylurea drug use points: These drugs also stimulate islet β cells secrete insulin, are ultra-short acting drug. Should immediately orally before meals, can play a role in taking an hour, the hypoglycemic effect of short duration, in patients with islet function completely destroyed or sulfonylurea failure, poor treatment of this class of drugs, hypoglycemia compared sulfonylureas less. 
          Biguanide drug use points: mainly inhibit the decomposition of glycogen and increase insulin sensitivity in peripheral tissues (such as muscle). This class of drugs alone does not cause low blood sugar, but can cause discomfort, gastrointestinal system and reduce appetite, it can reduce weight. 
          This class of drugs is particularly suitable for obese patients with type 2 diabetes. Meal should be taking phenformin can cause lactic acidosis, should be used with caution; metformin (such as Glucophage) is better, but is easy to hypoxia and liver and kidney function in patients with poor respiratory disease should not use. 
    -Glucosidase inhibitor administered drugs points: the main inhibit intestinal glycosidase 0c, not all result in the decomposition of carbohydrates in food in the intestine into a single paragraph of glucose, thereby delaying the intestinal absorption of glucose, reduce postprandial hyperglycemia . This class of drugs should be taken at the time of the first food to eat. This class of drugs alone does not cause low blood sugar, but early medication some people may appear mild diarrhea, bloating and other reactions, such as the first with a small dose and gradually increase the amount of 2-3 weeks, small intestine α- glucosidase gradually chyme carbohydrate-induced and recovery, the entire small intestine began to absorb glucose, when the symptoms of bloating can be improved or disappeared. 
          Insulin sensitizer drugs taking points: major increase in tissue sensitivity to insulin, insulin resistance in patients with good results. This class of drugs taken daily, the time fixed, the use of this class of drugs alone does not cause low blood sugar, but note that they have adverse effects on the liver, so liver function must be checked periodically during the medication.